{ CLINICAL PROGRESS Isotope
نویسنده
چکیده
Historical Review The use of isotopes in clinical cardiology was introduced by Blumgart, Yens, and Weiss, who used radium C and a cloud chamber to estimate the linear velocity of blood flow in an extensive series of studies starting in 1927.1, 2 Undoubtedly the major stimulus to the adoption of tracer technics came from the introduction of man-made radioisotopes after World War II. During the immediate postwar period several new methods were described. Quimby and Smith3 and Kety4 introduced the use of isotope clearance as a method of measuring the rate of blood flow to tissues. Prinzmetal and his collaborators used a Geiger counter placed over the precordium to follow the circulation of a bolus of radioactive blood through the right and left sides of the heart. They dubbed this procedure "radiocardiography."3 In 1953, WVaser and Hunzinger made the first attempts
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